Kolan Tüp Bebek Merkezi

• Şehremini Lisesi, İstanbul – 1995

  Ortadoğu Teknik Üniversitesi Biyoloji Bölümü, Ankara – 2000

2003 – 2005  Memorial Hastanesi Yardımcı Üreme Teknikleri ve Genetik Merkezi Androloji Laboratuvarı 

2005 – 2007 Memorial Hastanesi Yardımcı Üreme Teknikleri ve Genetik Merkezi – Androloji Laboratuvarı Sorumlusu

Haziran–Kasım 2007 HRS Ankara Kadın Doğum Hastanesi – Embriyoloji Laboratuvarı                                                            

Ocak 2008 – Kasım 2015 Memorial Hastanesi Yardımcı Üreme Teknikleri ve Genetik Merkezi – Embriyoloji Laboratuvarı

Kasım 2015 – Kasım 2017 Şişli Kolan International Hospital ÜYTE Laboratuvarı sorumlusu

Kasım 2017 – Şubat 2018  LIV Hospital Ulus Hastanesi ÜYTE Laboratuvarı Sorumlusu

Şubat 2018 – Şişli Kolan International Hospital ÜYTE Laboratuvarı sorumlusu

(2015)  Y. Kumtepe Colakoglu, M. Cetinkaya, C. Pirkevi, Z. Atayurt, H. Yelke, A. Karahasanoglu, H. Akbas1, S. Kahraman. Predicting live birth relies on different kinetic parameters depending on embryo transfer day. European Society of Human Reproduction and Embryology (ESHRE). Portugal, 14 to 17 June 2015

(2015)  C. Pirkevi, M. Cetinkaya, Y. Kumtepe Colakoglu, Z. Atayurt, H. Yelke, A.P. Cil, S. Kahraman. Is everything about the morula? The time to achieve a morula and the period at which the embryo stays a morula predict implantation. European Society of Human Reproduction and Embryology (ESHRE). Portugal, 14 to 17 June 2015

(2015)  G. Koksal, M. Cetinkaya, C. Pirkevi, Z. Atayurt, Y. Kumtepe Colakoglu, H. Yelke, M. Aygun, H. Akbas, S. Kahraman. Morphokinetic data obtained until day 2 are not sufficient to predict blastocyst formation and quality. European Society of Human Reproduction and Embryology (ESHRE). Portugal, 14 to 17 June 2015

(2015)  A.P. Cil1, S. Selcuk1, Z. Atayurt1, H. Yelke1, Y. Kumtepe1, S. Kahraman. Blastocyst development and pregnancy outcome of the frozen- embryo transfers are similar after GnRH agonist or HCG triggerring in patients at risk of OHSS. European Society of Human Reproduction and Embryology (ESHRE). Portugal, 14 to 17 June 2015

2015) Mehmet Ali Tufekci, Mehmet Murad Basar, Zafer Atayurt, Tugba Senel, Semra Kahraman. A comparison of IVF Outcomes of Intracytoplasmic sperm injection testicular or frojen-thawed testicular spermatozoa. AUA Annual Meeting. May 15 – 19, 2015, New Orleans, LA, USA

(2014) C. Pirkevi, M. Cetinkaya, Y. Kumtepe Colakoglu, Z. Atayurt, H. Yelke, S. Kahraman.Cleavage synchronicity thresholds derived from aneuploid embryos predict embryo implantationand live birth in an infertile cohort without PGS.Europan Society of Human Reproduction and Embryology (ESHRE), 29 June to 2 July 2014, Munich – Germany

(2014) M. Cetinkaya, C. Pirkevi, Y. Kumtepe Colakoglu, Z. Atayurt, H. Yelke, S. Kahraman. The synchronicity of mitotic divisions predicts embryo implantation and live birth. Europan Society of Human Reproduction and Embryology (ESHRE), 29 June to 2 July 2014, Munich – Germany

(2014) H. Yelke, Y. Kumtepe, Z. Atayurt, S. Yildiz, C. Pirkevi, H.A. Tac, C.G. Ekmekci, M. Cetinkaya, S. Kahraman. Is it obligatory to apply trophectoderm biopsy on the fifth day. Europan Society of Human Reproduction and Embryology (ESHRE), 29 June to 2 July 2014, Munich – Germany

(2013) M. Cetinkaya, C. Pirkevi, H. Yelke, Y. Kumtepe, Z. Atayurt, S. Kahraman. An additive model using morphokinetics to predict embryos of highest implantation potential. Europan Society of Human Reproduction and Embryology (ESHRE), 07 – 10 July 2013, London

(2013) C. Pirkevi, M. Cetinkaya, H. Yelke, Y. Kumtepe, Z. Atayurt, S. Kahraman. Synchronicity of cleavage cycles predicts blastocyst formation and quality. Europan Society of Human Reproduction and Embryology (ESHRE), 07 – 10 July 2013, London

/2012) S. Milik, C. Pirkevi, Z. Atayurt, S. Yazici, H. Yelke, S. Kahraman. Comparison of sperm immobilization in sperm slow vs. PVP in intracytoplasmic morphologically selected sperm injection. European Society of Human Reproduction & Embryology (ESHRE). July 1 – 4, 2012, Istanbul, Turkey

(2012) H. Yelke, Z. Atayurt, S. Yildiz, S. Unal, Y. Kumtepe, S. Kahraman. Is it possible to decrease the negative effect of poor sperm on infertility by the use of IMSI? European Society of Human Reproduction & Embryology (ESHRE). July 1 – 4, 2012, Istanbul, Turkey

(2012) C. Pirkevi, Z. Atayurt, H. Yelke, S. Kahraman. Quality control is definitely the key for success in IVF laboratories. European Society of Human Reproduction & Embryology (ESHRE). July 1 – 4, 2012, Istanbul, Turkey

(2012) Z.Atayurt, H.Yelke, S.Unal, Y.Kumtepe, S.Yıldız

Human embryo vitrification with home-made or commercial solutions: how quality of vitrification solution affects post thaw embryo quality and clinical results. 28th Annual Meeting of ESHRE – Istanbul 2012

(2010) G.Altin, S.Unal, H.Yelke, Y.Kumtepe, Z.Atayurt, S.Milik, C.Beyazyürek, C.Cınar, G.Karlikaya, S.Kahraman. Complete Or Partıal Correctıon Of Aneuploıdıc Embryos On Day 3 Formıng Hatchıng/Hatched Blastocysts on Day 5. 10th International Congress Preimplantation Genetic Diagnosis. May 5-8, 2010, Montpellier, France

(2010) G.Altin, S.Unal, H.Yelke, Y.Kumtepe, Z.Atayurt, S.Milik, C.Beyazyürek, C.Cınar, G.Karlikaya, S.Kahraman. Complete Or Partıal Correctıon Of Aneuploıdıc Embryos On Day 3 Formıng Hatchıng/Hatched Blastocysts on Day 5. 10th International Congress Preimplantation Genetic Diagnosis. May 5-8, 2010, Montpellier, France

(2009) G. Altin, S. Milik, Z.N. Candan, H. Yelke, S. Unal, Y. Kumtepe, Z. Atayurt and S. Kahraman. Comparing the developmental competency of chromosomally normal and abnormal embryos biopsied on day 3. 9th International Conference on Preimplantation Genetics. Miami, Florida USA, April 23 – 25, 2009

(2008) Z.Atayurt, S.Unal, H.Yelke, Z.N.Candan, S.Kahraman

Autologous endometrial coculture: a promising technique to overcome recurrent implantation failure. Preliminary results from 647 cycles. 24th Annual Meeting of ESHRE – Barcelona 2008

(2008) Nur Dokuzeylül, Zafer Atayurt, Güvenç Karlıkaya, Zafer Candan, Semra Kahraman. Şiddetli Erkek Faktörü Olan Tekrarlayan İmplantasyon Başarısızlığı Olgularında Morfolojik Olarak Seçilmiş Sperm Mikroenjeksiyonunun Embriyo Gelişimi ve Gebelik sonuçları Üzerine Etkisi: Erken Sonuçlar. 16 – 19 Ekim TSRM 2008 Antalya

(2007) Z.Atayurt, S. Sertyel, H. Karagözoğlu, N. Findikli, S. Unal, S. Kahraman. Endometrial co-culture: an effective culture system for pre-implantation genetic diagnosis? 23rd Annual Meeting of the ESHRE, Lyon, France, 1–4 July 2007

(2005) S. Sertyel, H. Karagozoglu, S. Unal, Z. Atayurt, U. Kutlu, G. Karlikaya, E. Oral, O. Akcin, N. Findikli, S. Kahraman. Endometrial co-culture can be an effective culture system in cases with preimplantation genetic diagnosis for recurrent implantation failure. 13th World Congress on in-vitro Fertilization Assisted Reproduction & Genetics, Istanbul, Turkey, May 26-29, 2005.

(2005) Sertyel S, Unal S, Yelke H, Atayurt Z, Findikli N, Karlikaya G, Fiorentino F, Kahraman S. The stage of the embryo but not the number of cells removed may affect embryo development after biopsy. Sixth International Symposium on Preimplantation Genetics 2005. London, UK. May 19–21, 2005.

(2004) E. Enginsu, N. Findikli, S. Sertyel, S. Melil, Z. Atayurt, G. Karlikaya, F. Vanlioglu, S. Kahraman. Increasing hyaluronan concentrations in the embryo transfer medium has no effect on ART outcome. 20th Annual Meeting of the ESHRE, Berlin, Germany, 27–30 June 2004

YAYINLAR :

A Possible Beneficial Effect of Artificial Sperm Hyperactivation in Cases With FrozenPossible Beneficial Effect of Artificial Sperm Hyperactivation in Cases With Frozen/Thawed Human Spermatozoa .(2005)  Fertility and Sterility , Volume 84 , Pages S371 – S371 S . Sertyel , S . Unal , Z . Atayurt , H . Yelke , S . Ozkan , S . Kahraman/Thawed Human Spermatozoa Fertility and Sterility , Volume 84 , Pages S371 – S371 S . Sertyel ,S . Unal , Z . Atayurt , H . Yelke , S . Ozkan , S . Kahraman

BİLİMSEL TOPLANTI VE KONFERANSLAR (Organizasyon):

8th Hands-on Workshop on PGD for Genetic & Chromosomal Disorders by Blastocyst Biopsy, Istanbul Memorial Hospital, May 7-9, 2015, Istanbul, Turkey – SORUMLU EĞİTMEN

7th Hands-On Workshop on PGD for Genetic and Chromosomal Disorders by Blastocyst Biopsy. Istanbul Memorial Hospital, May 04-06, 2014, Istanbul, Turkey – SORUMLU EĞİTMEN

6th Hands-On Workshop on PGD for Genetic and Chromosomal Disorders by Blastocyst Biopsy. Istanbul Memorial Hospital, May 12-14, 2013, Istanbul, Turkey

5th Hands-On Workshop On PGD For Genetıc And Chromosomal Dısorders By Blastocyst Bıopsy,PGDIS Workshop: May  2012 Istanbul, Turkey

4th Hands-On Workshop On PGD For Genetıc And Chromosomal Dısorders By Blastocyst Bıopsy,PGDIS Workshop: May 16–18, 2011 Istanbul, Turkey

Art:Experimental Bases For Improvıng Outcomes For The Benefit Of Patients: 19 Şubat-20 Şubat, 2010 Istanbul, Turkey

3nd Hands-On Workshop On PGD For Genetıc And Chromosomal Dısorders By Blastocyst Bıopsy PGDIS Workshop: May 10–12, 2010 Istanbul, Turkey

2nd Hands-On Workshop On PGD Of Genetıc And Chromosomal Dısorders By Blastomere & Trophectoderm Bıopsy: February 26-28, 2009, Istanbul, Turkey

1sthands-On Workshop On PGD Of Genetıc And Chromosomal Dısorders By Blastomere And Trophectoderm Bıopsy: 28 – 30 April 2008, Istanbul, Turkey

2nd Internatıonal Conference On Scıence And Moral Phılosophy (Ethıcs) Of Assısted Human Reproductıon: 28-29 April 2006, Istanbul, Turkey

Current Technıques And Future Trends On Gamete And Embryo Manıpulatıon: 4-5 March 2006, Istanbul, Turkey

Üremeye Yardımcı Tedavi Yöntemleri Eğitim Sertifikası – 2008

Üremeye Yardımcı Tedavi Yöntemleri Eğitim Sertifikası(ICSI yeterlilik) – 2008

IVF LABORATUVARI İŞLEMLERİ YETKİNLİĞİ:

* ICSI, IVF, IMSI

* AHA (Assisted Hatching Teknikleri)
* OPU, Oosit ve kümülüs kütle değerlendirilmesi, denudasyon
* Pronükleus yapıların değerlendirilmesi
* Embriyo gelişim değerlendirilmesi(Mikroskopik ve Time-lapse izleme değerlendirmesi)
* Embriyo transferi
* Embriyo Dondurma-Çözme (Vitrifikasyon/yavaş dondurma)
* Kültür ortamı hazırlanması

* Endometrial ko-kültür

* Polar body, blastomer, trofektoderm biyopsi İşlemleri

* Semen Analizi, sperm fonksiyon ve kalite testleri(Acridine Orange, TUNEL, Halosperm)
* Sperm Morfoloji değerlendirmesi (Kruger, MSOME)
* Sperm hazırlama teknikleri(Ejakulat ve testiküler)
* Sperm canlılık testi(Eosin-Y, HOST)
* Sperm Dondurma-Çözme Teknikleri (Vitrifikasyon/yavaş dondurma)

* Laboratuvar kalite kontrol uygulamaları

* IVF laboratuvarı akreditasyon (ISO 15189)

* IVF laboratuvar kurulumu ve işletimi (laboratuvar yerleşimi projelendirme, donanım ve sarf malzeme bilgisi, firma ilişkileri)